OBJECTIVE: To study predictive factors influencing the multiple pregnancy rate in in vitro fertilization (IVF). STUDY DESIGN:
Retrospective study. RESULTS: In 1,736 IVF cycles, 453 pregnancies occurred. The rate of singleton, twin and triplet pregnancies
was 44%, 22% and 4.5%, respectively. Eighty-one percent of these clinical pregnancies ended with a delivery, giving a "take-home
baby" rate of 23.8%/oocyte retrieval. As expected, a statistically significant positive correlation was found between the
number and quality of embryos replaced and the occurrence of multiple pregnancies. A statistically significant correlation
was also found when parameters such as age, stimulation parameters and embryo characteristics were incorporated into the analysis.
This correlation was different for singleton, twin and triplet pregnancies. CONCLUSION: Based on the findings of this study,
in patients with a good prognosis for IVF outcome, only two embryos of good quality should be replaced regardless of the maternal
age or number of IVF attempts.
Informations complémentaires
Departement :
UCL - "MD/GYPE - Département de gynécologie, d'obstétrique et de pédiatrie"